Nonhomologous Recombination between Defective Poliovirus and Coxsackievirus Genomes Suggests a New Model of Genetic Plasticity for Picornaviruses

Most of the circulating vaccine-derived polioviruses (cVDPVs) implicated in poliomyelitis outbreaks in Madagascar have been shown to be recombinants between the type 2 poliovirus (PV) strain of the oral polio vaccine (Sabin 2) and another species C human enterovirus (HEV-C), such as type 17 coxsacki...

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Main Authors: Holmblat, Barbara, Jégouic, Sophie, Muslin, Claire, Blondel, Bruno, Joffret, Marie-Line, Delpeyroux, Francis
Format: Artigo
Jezik:Inglês
Izdano: American Society of Microbiology 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128350/
https://ncbi.nlm.nih.gov/pubmed/25096874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01119-14
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