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Salvinorin A analogs and other kappa opioid receptor compounds as treatments for cocaine abuse

Acute activation of κ opioid receptors produces anti-addictive effects by regulating dopamine levels in the brain. Unfortunately, classic κ opioid agonists have undesired side effects such as sedation, aversion and depression which restrict their clinical use. Salvinorin A (Sal A), a novel κ opioid...

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Bibliographic Details
Main Authors: Kivell, Bronwyn M, Ewald, Amy WM, Prisinzano, Thomas E
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128345/
https://ncbi.nlm.nih.gov/pubmed/24484985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-420118-7.00012-3
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