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The Effects of GATA-1 and NF-E2 Deficiency on Bone Biomechanical, Biochemical, and Mineral Properties

Mice deficient in GATA-1 or NF-E2, transcription factors required for normal megakaryocyte (MK) development, have increased numbers of MKs, reduced numbers of platelets, and a striking high bone mass phenotype. Here, we show the bone geometry, microarchitecture, biomechanical, biochemical, and miner...

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Detalhes bibliográficos
Main Authors: Kacena, Melissa A., Gundberg, Caren M., Kacena, William J., Landis, William J., Boskey, Adele L., Bouxsein, Mary L., Horowitz, Mark C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128339/
https://ncbi.nlm.nih.gov/pubmed/23359245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24322
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