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Clinical Implementation of Germline Cancer Pharmacogenetic Variants during the Next-Generation Sequencing Era
Over 100 FDA-approved medications include pharmacogenetic biomarkers in the drug label, many with cancer indications referencing germline DNA variations. With the advent of next-generation sequencing (NGS) and its rapidly increasing uptake into cancer research and clinical practice, an enormous amou...
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2013
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4128332/ https://ncbi.nlm.nih.gov/pubmed/24136381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2013.214 |
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