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Clinical Implementation of Germline Cancer Pharmacogenetic Variants during the Next-Generation Sequencing Era

Over 100 FDA-approved medications include pharmacogenetic biomarkers in the drug label, many with cancer indications referencing germline DNA variations. With the advent of next-generation sequencing (NGS) and its rapidly increasing uptake into cancer research and clinical practice, an enormous amou...

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Autors principals: Gillis, Nancy K., Patel, Jai N., Innocenti, Federico
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128332/
https://ncbi.nlm.nih.gov/pubmed/24136381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2013.214
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