Surface expression of the hRSV nucleoprotein impairs immunological synapse formation with T cells

Human respiratory syncytial virus (hRSV) is the leading cause of bronchiolitis and pneumonia in young children worldwide. The recurrent hRSV outbreaks and reinfections are the cause of a significant public health burden and associate with an inefficient antiviral immunity, even after disease resolut...

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Bibliographic Details
Main Authors: Céspedes, Pablo F., Bueno, Susan M., Ramírez, Bruno A., Gomez, Roberto S., Riquelme, Sebastián A., Palavecino, Christian E., Mackern-Oberti, Juan Pablo, Mora, Jorge E., Depoil, David, Sacristán, Catarina, Cammer, Michael, Creneguy, Alison, Nguyen, Tuan H., Riedel, Claudia A., Dustin, Michael L., Kalergis, Alexis M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2014
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128097/
https://ncbi.nlm.nih.gov/pubmed/25056968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400760111
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