The effect of inflammatory cell-derived MCP-1 loss on neuronal survival during chronic neuroinflammation

Intracranial implants elicit neurodegeneration via the foreign body response (FBR) that includes BBB leakage, macrophage/microglia accumulation, and reactive astrogliosis, in addition to neuronal degradation that limit their useful lifespan. Previously, monocyte chemoattractant protein 1 (MCP-1, als...

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Bibliografiske detaljer
Main Authors: Sawyer, Andrew J., Tian, Weiming, Saucier-Sawyer, Jennifer K., Rizk, Paul J., Saltzman, W. Mark, Bellamkonda, Ravi, Kyriakides, Themis R.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128094/
https://ncbi.nlm.nih.gov/pubmed/24881026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.05.008
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