The effect of hyperpolarization-activated cyclic nucleotide-gated ion channel inhibitors on the vagal control of guinea pig airway smooth muscle tone

BACKGROUND AND PURPOSE: Subtypes of the hyperpolarization-activated cyclic nucleotide-gated (HCN) family of cation channels are widely expressed on nerves and smooth muscle cells in many organ systems, where they serve to regulate membrane excitability. Here we have assessed whether HCN channel inhi...

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Bibliografiske detaljer
Main Authors: McGovern, Alice E, Robusto, Jed, Rakoczy, Joanna, Simmons, David G, Phipps, Simon, Mazzone, Stuart B
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2014
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128062/
https://ncbi.nlm.nih.gov/pubmed/24762027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12745
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