NPY/Y(1) receptor-mediated vasoconstrictory and proliferative effects in pulmonary hypertension

BACKGROUND AND PURPOSE: Pulmonary arteries (PAs) are innervated, but little is known about the role of neuronal axis in pulmonary hypertension (PH). Here, we have examined the role of the neuropeptide Y (NPY) and its Y(1) receptor in PH pathogenesis. EXPERIMENTAL APPROACH: NPY was localized by immun...

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Detalhes bibliográficos
Main Authors: Crnkovic, S, Egemnazarov, B, Jain, P, Seay, U, Gattinger, N, Marsh, L M, Bálint, Z, Kovacs, G, Ghanim, B, Klepetko, W, Schermuly, R T, Weissmann, N, Olschewski, A, Kwapiszewska, G
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128051/
https://ncbi.nlm.nih.gov/pubmed/24779394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12751
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