טוען...

Nucleoside transporters and human organic cation transporter 1 determine the cellular handling of DNA-methyltransferase inhibitors

BACKGROUND AND PURPOSE: Inhibitors of DNA methyltransferases (DNMTs), such as azacytidine, decitabine and zebularine, are used for the epigenetic treatment of cancer. Their action may depend upon their translocation across the plasma membrane. The aim of this study was to identify transporter protei...

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מידע ביבליוגרפי
Main Authors: Arimany-Nardi, C, Errasti-Murugarren, E, Minuesa, G, Martinez-Picado, J, Gorboulev, V, Koepsell, H, Pastor-Anglada, M
פורמט: Artigo
שפה:Inglês
יצא לאור: Blackwell Publishing Ltd 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128049/
https://ncbi.nlm.nih.gov/pubmed/24780098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12748
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