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Identification and Characterization of Novel Inhibitors of Mammalian Aspartyl Aminopeptidase
Aspartyl aminopeptidase (DNPEP) has been implicated in the control of angiotensin signaling and endosome trafficking, but its precise biologic roles remain incompletely defined. We performed a high-throughput screen of ∼25,000 small molecules to identify inhibitors of DNPEP for use as tools to study...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The American Society for Pharmacology and Experimental Therapeutics
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4127928/ https://ncbi.nlm.nih.gov/pubmed/24913940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.093070 |
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