A Phase 2 Trial of Flavopiridol (Alvocidib) and Cisplatin in Platin-Resistant Ovarian and Primary Peritoneal Carcinoma: MC0261

PURPOSE: Based upon promising preclinical and phase 1 trial results, combined flavopiridol and cisplatin therapy was evaluated in patients with ovarian and primary peritoneal cancers. METHODS: A two cohort phase 2 trial of cisplatin (60 mg/m(2) IV) immediately followed by flavopiridol (100 mg/m(2) I...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Bible, Keith C., Peethambaram, Prema P., Oberg, Ann L., Maples, William, Groteluschen, David L., Boente, Matthew, Burton, Jill K., Gomez Dahl, Leigh C., Tibodeau, Jennifer D., Isham, Crescent R., Maguire, Jacie L., Shridhar, Viji, Kukla, Andrea K., Voll, Kalli J., Mauer, Mathew J., Colevas, Alexander D., Wright, John, Doyle, L. Austin, Erlichman, Charles
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2012
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127485/
https://ncbi.nlm.nih.gov/pubmed/22664059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2012.05.030
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