Development of positive antinuclear antibodies and rheumatoid factor in systemic juvenile idiopathic arthritis points toward an autoimmune phenotype later in the disease course

BACKGROUND: Systemic juvenile idiopathic arthritis (sJIA) is commonly considered an autoinflammatory disease. However, sJIA patients may develop aggressive arthritis without systemic inflammation later in the disease, resembling an autoimmune phenotype similar to other subtypes of JIA. The objective...

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Autores principales: Hügle, Boris, Hinze, Claas, Lainka, Elke, Fischer, Nadine, Haas, Johannes-Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Short Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127434/
https://ncbi.nlm.nih.gov/pubmed/25114627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1546-0096-12-28
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