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“Soft” Calcium Crosslinks Enable Highly Efficient Gene Transfection Using TAT Peptide

PURPOSE: Typically, low molecular weight cationic peptides or polymers exhibit poor transfection efficiency due to an inability to condense plasmid DNA into small nanoparticles. Here, efficient gene delivery was attained using TAT/pDNA complexes containing calcium crosslinks. METHODS: Electrostatic...

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Detalhes bibliográficos
Main Authors: Baoum, Abdulgader, Xie, Sheng-Xue, Fakhari, Amir, Berkland, Cory
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127430/
https://ncbi.nlm.nih.gov/pubmed/19789962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-009-9976-1
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