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Ruscogenin Ameliorates Experimental Nonalcoholic Steatohepatitis via Suppressing Lipogenesis and Inflammatory Pathway

The aim of the study was to investigate the protective effects of ruscogenin, a major steroid sapogenin in Ophiopogon japonicus, on experimental models of nonalcoholic steatohepatitis. HepG2 cells were exposed to 300 μmol/l palmitic acid (PA) for 24 h with the preincubation of ruscogenin for another...

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Détails bibliographiques
Auteurs principaux: Lu, Hung-Jen, Tzeng, Thing-Fong, Liou, Shorong-Shii, Chang, Chia Ju, Yang, Cheng, Wu, Ming-Chang, Liu, I-Min
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127260/
https://ncbi.nlm.nih.gov/pubmed/25136608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/652680
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