Ruscogenin ameliorates diabetic nephropathy by its anti-inflammatory and anti-fibrotic effects in streptozotocin-induced diabetic rat

BACKGROUND: Ruscogenin is a major steroid sapogenin in the traditional Chinese herb Ophiopogon japonicus that have multiple bioactivities. Recent studies have demonstrated that ruscogenin is involved in down-regulation of intercellular adhesion molecule-1 (ICAM-1) and nuclear factor-κB (NF-κB) activ...

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Main Authors: Lu, Hung-Jen, Tzeng, Thing-Fong, Liou, Shorong-Shii, Da Lin, Sheng, Wu, Ming-Chang, Liu, I-Min
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986976/
https://ncbi.nlm.nih.gov/pubmed/24666993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6882-14-110
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