Dynamic changes in intracellular ROS levels regulate airway basal stem cell homeostasis through Nrf2-dependent Notch signaling

Airways are exposed to myriad environmental and damaging agents such as reactive oxygen species (ROS), which also have physiological roles as signaling molecules that regulate stem cell function. However, the functional significance of both steady and dynamically changing ROS levels in different ste...

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Hlavní autoři: Paul, MK, Bisht, B, Darmawan, DO, Chiou, R, Ha, VL, Wallace, WD, Chon, AC, Hegab, AE, Grogan, T, Elashoff, DA, Alva-Ornelas, JA, Gomperts, BN
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127166/
https://ncbi.nlm.nih.gov/pubmed/24953182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2014.05.009
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