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New molecular engineering approaches for crystallographic studies of large RNAs
Crystallization of RNAs with complex three-dimensional architectures remains a formidable experimental challenge. We review a number of successful heuristics involving engineering of the target RNAs to facilitate crystal contact formation, such as those that enabled the crystallization and structure...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4127099/ https://ncbi.nlm.nih.gov/pubmed/24607443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2014.02.001 |
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