PROGRESSIVE CHANGE OF INTRA-ISLET GLP-1 PRODUCTION DURING DIABETES DEVELOPMENT

BACKGROUND: Glucagon-like Peptide 1 (GLP-1) and glucagon shares the same precursor molecule proglucagon, but each arises from a distinct posttranslational process in a tissue-specific manner. Recently it has been shown that GLP-1 is co-expressed with glucagon in pancreatic islet cells. This study wa...

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Bibliografiske detaljer
Main Authors: O’Malley, Thomas J., Fava, Genevieve E., Zhang, Yanqing, Fonseca, Vivian A., Wu, Hongju
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126896/
https://ncbi.nlm.nih.gov/pubmed/24510483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dmrr.2534
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