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Milbemycin A4 oxime as a probe of azole transport in Candida glabrata

Azole resistance in Candida glabrata, a pathogenic yeast, has prompted studies of compounds that have therapeutic potential by reversing azole resistance. Milbemycin A4 oxime blocked azole efflux and enhanced azole susceptibility four-fold in 28 clinical isolates of C. glabrata. Specificity of the m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Walker, Bryan, Izumikawa, Koichi, Tsai, Huie-Fung, Bennett, John E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126866/
https://ncbi.nlm.nih.gov/pubmed/24838041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1567-1364.12164
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