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Insight Derived from Molecular Dynamics Simulations into Molecular Motions, Thermodynamics and Kinetics of HIV-1 gp120

Although the crystal structures of the HIV-1 gp120 core bound and pre-bound by CD4 are known, the details of dynamics involved in conformational equilibrium and transition in relation to gp120 function have remained elusive. The homology models of gp120 comprising the N- and C-termini and loops V3 a...

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Detalhes bibliográficos
Main Authors: Sang, Peng, Yang, Li-Quan, Ji, Xing-Lai, Fu, Yun-Xin, Liu, Shu-Qun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126740/
https://ncbi.nlm.nih.gov/pubmed/25105502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104714
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