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Of Worms and Men: HLH-30 and TFEB Regulate Tolerance to Infection
In this issue of Immunity, Visvikis et al. (2014) use the model host Caenorhabditis elegans to discover a role in innate immunity for the basic helix-loop-helix transcription faction, HLH-30. The finding inspires study of the mammalian ortholog TFEB, in which a similar role in immune response is asc...
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Autori principali: | , |
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Natura: | Artigo |
Lingua: | Inglês |
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2014
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Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4126603/ https://ncbi.nlm.nih.gov/pubmed/24950206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.06.002 |
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