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Of Worms and Men: HLH-30 and TFEB Regulate Tolerance to Infection

In this issue of Immunity, Visvikis et al. (2014) use the model host Caenorhabditis elegans to discover a role in innate immunity for the basic helix-loop-helix transcription faction, HLH-30. The finding inspires study of the mammalian ortholog TFEB, in which a similar role in immune response is asc...

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Sonraí Bibleagrafaíochta
Main Authors: Tiller, George R., Garsin, Danielle A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126603/
https://ncbi.nlm.nih.gov/pubmed/24950206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.06.002
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