Glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) expression correlates with malignant choline phospholipid metabolite profiles in human breast cancer

Altered choline phospholipid metabolism is a hallmark of cancer, leading to malignant choline metabolite profiles consisting of low glycerophosphocholine (GPC) and high phosphocholine (PC) in human breast cancers. Glycerophosphocholine phosphodiesterase (GPC-PDE) catalyzes the degradation of GPC to...

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Autori principali: Cao, Maria D., Döpkens, Mailin, Krishnamachary, Balaji, Vesuna, Farhad, Gadiya, Mayur M., Loenning, Per E., Bhujwalla, Zaver M., Gribbestad, Ingrid S., Glunde, Kristine
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126590/
https://ncbi.nlm.nih.gov/pubmed/22279038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.2766
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