Testing the Key Assumption of Heritability Estimates Based on Genome-wide Genetic Relatedness

Comparing genetic and phenotypic similarity among unrelated individuals seems a promising way to quantify the genetic component of traits while avoiding the problematic assumptions plaguing twin- and other kin-based estimates of heritability. One approach uses a Genetic Relatedness Estimation throug...

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Autores principales: Conley, Dalton, Siegal, Mark L., Domingue, Benjamin, Harris, Kathleen Mulan, McQueen, Matthew, Boardman, Jason
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126504/
https://ncbi.nlm.nih.gov/pubmed/24599117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jhg.2014.14
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