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Helical Organization of Blood Coagulation Factor VIII on Lipid Nanotubes

Cryo-electron microscopy (Cryo-EM)(1) is a powerful approach to investigate the functional structure of proteins and complexes in a hydrated state and membrane environment(2). Coagulation Factor VIII (FVIII)(3) is a multi-domain blood plasma glycoprotein. Defect or deficiency of FVIII is the cause f...

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Detalhes bibliográficos
Main Authors: Miller, Jaimy, Dalm, Daniela, Koyfman, Alexey Y., Grushin, Kirill, Stoilova-McPhie, Svetla
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126079/
https://ncbi.nlm.nih.gov/pubmed/24961276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51254
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