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Domain Organization of Membrane-Bound Factor VIII

Factor VIII (FVIII) is the blood coagulation protein which when defective or deficient causes for hemophilia A, a severe hereditary bleeding disorder. Activated FVIII (FVIIIa) is the cofactor to the serine protease factor IXa (FIXa) within the membrane-bound Tenase complex, responsible for amplifyin...

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Bibliografiske detaljer
Main Authors: Stoilova-McPhie, Svetla, Lynch, Gillian C., Ludtke, Steven, Pettitt, B. Montgomery
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090243/
https://ncbi.nlm.nih.gov/pubmed/23616213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.22199
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