The mode of action of aspirin-like drugs: effect on inducible nitric oxide synthase.

Nitric oxide synthesized by inducible nitric oxide synthase (iNOS) has been implicated as a mediator of inflammation in rheumatic and autoimmune diseases. We report that exposure of lipopolysaccharide-stimulated murine macrophages to therapeutic concentrations of aspirin (IC50 = 3 mM) and hydrocorti...

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Библиографические подробности
Главные авторы: Amin, A R, Vyas, P, Attur, M, Leszczynska-Piziak, J, Patel, I R, Weissmann, G, Abramson, S B
Формат: Artigo
Язык:Inglês
Опубликовано: 1995
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC41259/
https://ncbi.nlm.nih.gov/pubmed/7544010
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