The mode of action of aspirin-like drugs: effect on inducible nitric oxide synthase.

Nitric oxide synthesized by inducible nitric oxide synthase (iNOS) has been implicated as a mediator of inflammation in rheumatic and autoimmune diseases. We report that exposure of lipopolysaccharide-stimulated murine macrophages to therapeutic concentrations of aspirin (IC50 = 3 mM) and hydrocorti...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Amin, A R, Vyas, P, Attur, M, Leszczynska-Piziak, J, Patel, I R, Weissmann, G, Abramson, S B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41259/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7544010/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.17.7926
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