Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting

AIM: To study if T-cell activation related to portasystemic shunting causes osteoclast-mediated bone loss through RANKL-dependent pathways. We also investigated if T-cell inhibition using rapamycin would protect against bone loss in rats. METHODS: Portasystemic shunting was performed in male Sprague...

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Bibliographische Detailangaben
Hauptverfasser: van der Merwe, Schalk W, Conradie, Maria M, Bond, Robert, Olivier, Brenda J, Fritz, Elongo, Nieuwoudt, Martin, Delport, Rhena, Slavik, Tomas, Engelbrecht, Gert, Kahn, Del, Shephard, Enid G, Kotze, Maritha J, de Villiers, Nico P, Hough, Stephen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Baishideng Publishing Group Co., Limited 2006
Schlagworte:
Basic Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125637/
https://ncbi.nlm.nih.gov/pubmed/16874862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v12.i28.4504
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