Gene–gene interactions in breast cancer susceptibility

There have been few definitive examples of gene–gene interactions in humans. Through mutational analyses in 7325 individuals, we report four interactions (defined as departures from a multiplicative model) between mutations in the breast cancer susceptibility genes ATM and CHEK2 with BRCA1 and BRCA2...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Turnbull, Clare, Seal, Sheila, Renwick, Anthony, Warren-Perry, Margaret, Hughes, Deborah, Elliott, Anna, Pernet, David, Peock, Susan, Adlard, Julian W., Barwell, Julian, Berg, Jonathan, Brady, Angela F., Brewer, Carole, Brice, Glen, Chapman, Cyril, Cook, Jackie, Davidson, Rosemarie, Donaldson, Alan, Douglas, Fiona, Greenhalgh, Lynn, Henderson, Alex, Izatt, Louise, Kumar, Ajith, Lalloo, Fiona, Miedzybrodzka, Zosia, Morrison, Patrick J, Paterson, Joan, Porteous, Mary, Rogers, Mark T., Shanley, Susan, Walker, Lisa, Ahmed, Munaza, Eccles, Diana, Evans, D. Gareth, Donnelly, Peter, Easton, Douglas F., Stratton, Michael R., Rahman, Nazneen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Association Studies Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125627/
https://ncbi.nlm.nih.gov/pubmed/22072393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr525
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge