ロード中...

PTEN-DEFICIENT TUMORS DEPEND ON AKT2 FOR MAINTENANCE AND SURVIVAL

Loss of PTEN is a common event in many cancers and leads to hyperactivation of the PI 3-K/Akt signaling pathway. The mechanisms by which Akt isoforms mediate signaling to phenotypes associated with PTEN-inactivation in cancer have not been defined. Here we show that Akt2 is exclusively required for...

詳細記述

保存先:
書誌詳細
主要な著者: Chin, Y. Rebecca, Yuan, Xin, Balk, Steven P., Toker, Alex
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125464/
https://ncbi.nlm.nih.gov/pubmed/24838891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-13-0873
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!