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Function of Akt/PKB Signaling to Cell Motility, Invasion and the Tumor Stroma in Cancer

The serine/threonine protein kinase Akt is a major signal transducer of the phosphoinositide 3-kinase (PI 3-K) pathway in all cells and tissues and plays a pivotal role in the maintenance of cellular processes including cell growth, proliferation, survival and metabolism. The frequent aberrant activ...

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Detalhes bibliográficos
Main Authors: Chin, Y. Rebecca, Toker, Alex
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719559/
https://ncbi.nlm.nih.gov/pubmed/19110052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2008.11.015
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