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Epigenetic modification of the FoxP3 TSDR in HAM/TSP decreases the functional suppression of Tregs
HTLV-1 is a human retrovirus that is associated with the neuroinflammatory disorder HTLV-1 associated myelopathy/ tropical spastic paraparesis (HAM/TSP). In these patients, HTLV-1 is primarily found in the CD4(+)CD25(+) T cell subset (Regulatory T cells:Tregs), which is responsible for peripheral im...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4125438/ https://ncbi.nlm.nih.gov/pubmed/24845974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-014-9547-z |
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