NSD3-NUT Fusion Oncoprotein in NUT Midline Carcinoma: Implications for a Novel Oncogenic Mechanism

NUT midline carcinoma (NMC) is an aggressive subtype of squamous cell carcinoma that typically harbors BRD4/3-NUT fusion oncoproteins that block differentiation and maintain tumor growth. In 20% of cases NUT is fused to uncharacterized non-BRD gene(s). We established a new patient-derived NMC cell l...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: French, Christopher A., Rahman, Shaila, Walsh, Erica M., Kühnle, Simone, Grayson, Adlai R., Lemieux, Madeleine E., Grunfeld, Noam, Rubin, Brian P., Antonescu, Cristina R., Zhang, Songlin, Venkatramani, Rajkumar, Cin, Paola Dal, Howley, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125436/
https://ncbi.nlm.nih.gov/pubmed/24875858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-14-0014
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados