Comprehensive Identification of Single Nucleotide Polymorphisms Associated with Beta-lactam Resistance within Pneumococcal Mosaic Genes

Traditional genetic association studies are very difficult in bacteria, as the generally limited recombination leads to large linked haplotype blocks, confounding the identification of causative variants. Beta-lactam antibiotic resistance in Streptococcus pneumoniae arises readily as the bacteria ca...

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Detalhes bibliográficos
Main Authors: Chewapreecha, Claire, Marttinen, Pekka, Croucher, Nicholas J., Salter, Susannah J., Harris, Simon R., Mather, Alison E., Hanage, William P., Goldblatt, David, Nosten, Francois H., Turner, Claudia, Turner, Paul, Bentley, Stephen D., Parkhill, Julian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125147/
https://ncbi.nlm.nih.gov/pubmed/25101644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004547
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