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Targeting DNA repair pathways for cancer treatment: what's new?
Disruptions in DNA repair pathways predispose cells to accumulating DNA damage. A growing body of evidence indicates that tumors accumulate progressively more mutations in DNA repair proteins as cancers progress. DNA repair mechanisms greatly affect the response to cytotoxic treatments, so understan...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4125008/ https://ncbi.nlm.nih.gov/pubmed/24947262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon.14.60 |
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