Toll-like Receptor (TLR) variants are associated with infant HIV-1 acquisition and peak plasma HIV-1 RNA level

OBJECTIVE: We evaluated the association of single nucleotide polymorphisms (SNPs) in TLRs with infant HIV-1 acquisition and viral control. DESIGN: Infant HIV-1 outcomes were assessed in a Kenyan perinatal HIV-1 cohort. METHODS: Infants were genotyped for six candidate and 118 haplotype-tagging polym...

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Autori principali: BEIMA-SOFIE, Kristin M., BIGHAM, Abigail W., LINGAPPA, Jairam R., WAMALWA, Dalton, MACKELPRANG, Romel D., Bamshad, Michael J., MALECHE-OBIMBO, Elizabeth, RICHARDSON, Barbra A., JOHN-STEWART, Grace C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124859/
https://ncbi.nlm.nih.gov/pubmed/24037211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e3283629117
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