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A simple structure-based model for the prediction of HIV-1 co-receptor tropism
BACKGROUND: Human Immunodeficiency Virus 1 enters host cells through interaction of its V3 loop (which is part of the gp120 protein) with the host cell receptor CD4 and one of two co-receptors, namely CCR5 or CXCR4. Entry inhibitors binding the CCR5 co-receptor can prevent viral entry. As these drug...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4124776/ https://ncbi.nlm.nih.gov/pubmed/25120583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0381-7-14 |
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