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The long and winding road for the development of tasquinimod as an oral second-generation quinoline-3-carboxamide antiangiogenic drug for the treatment of prostate cancer

IMPORTANCE OF THE FIELD: Prostate cancer is the mostly commonly diagnosed non-skin cancer in males. The culmination of the last 70 years of clinical drug development has documented that androgen ablation plus taxane-based systemic chemotherapy enhances survival, but is not curative, in metastatic pr...

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Autore principale: Isaacs, John T
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124623/
https://ncbi.nlm.nih.gov/pubmed/20836618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543784.2010.514262
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