p27(kip1) haplo-insufficiency improves cardiac function in early-stages of myocardial infarction by protecting myocardium and increasing angiogenesis by promoting IKK activation

p27(kip1) (p27) is widely known as a potent cell cycle inhibitor in several organs, especially in the heart. However, its role has not been fully defined during the early phase of myocardial infarction (MI). In this study, we investigated the relationships between p27, vascular endothelial growth fa...

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Detalhes bibliográficos
Main Authors: Zhou, Ningtian, Fu, Yuxuan, Wang, Yunle, Chen, Pengsheng, Meng, Haoyu, Guo, Shouyu, Zhang, Min, Yang, Zhijian, Ge, Yingbin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124466/
https://ncbi.nlm.nih.gov/pubmed/25099287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05978
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