Trans-ethnic study confirmed independent associations of HLA-A*02:06 and HLA-B*44:03 with cold medicine-related Stevens-Johnson syndrome with severe ocular surface complications

Stevens-Johnson syndrome (SJS) and its severe variant, toxic epidermal necrolysis (TEN), are acute inflammatory vesiculobullous reactions of the skin and mucous membranes. Cold medicines including non-steroidal anti-inflammatory drugs and multi-ingredient cold medications are reported to be importan...

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Main Authors: Ueta, Mayumi, Kannabiran, Chitra, Wakamatsu, Tais Hitomi, Kim, Mee Kum, Yoon, Kyung-Chul, Seo, Kyoung Yul, Joo, Choun-Ki, Sangwan, Virender, Rathi, Varsha, Basu, Sayan, Shamaila, Almas, Lee, Hyo Seok, Yoon, Sangchul, Sotozono, Chie, Gomes, José Álvaro Pereira, Tokunaga, Katsushi, Kinoshita, Shigeru
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124463/
https://ncbi.nlm.nih.gov/pubmed/25099678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05981
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