HLA-A*02:06 and PTGER3 polymorphism exert additive effects in cold medicine-related Stevens–Johnson syndrome with severe ocular complications

We previously reported that PTGER3 (prostaglandin E receptor 3 (subtype EP3)) single-nucleotide polymorphisms (SNPs) were associated with Stevens–Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) with severe ocular complications (SOC). We also documented that approximately 80% of our SJS/TEN p...

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Enregistré dans:
Détails bibliographiques
Publié dans:Hum Genome Var
Auteurs principaux: Ueta, Mayumi, Tokunaga, Katsushi, Sotozono, Chie, Sawai, Hiromi, Yoon, Kyung-Chul, Kum Kim, Mee, Yul Seo, Kyoung, Joo, Choun-Ki, Tashiro, Kei, Kinoshita, Shigeru
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785539/
https://ncbi.nlm.nih.gov/pubmed/27081535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hgv.2015.23
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