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The transcriptional landscape of mouse beta cells compared to human beta cells reveals notable species differences in long non-coding RNA and protein-coding gene expression

BACKGROUND: Insulin producing beta cell and glucagon producing alpha cells are colocalized in pancreatic islets in an arrangement that facilitates the coordinated release of the two principal hormones that regulate glucose homeostasis and prevent both hypoglycemia and diabetes. However, this intrica...

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Detalhes bibliográficos
Main Authors: Benner, Christopher, van der Meulen, Talitha, Cacéres, Elena, Tigyi, Kristof, Donaldson, Cynthia J, Huising, Mark O
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124169/
https://ncbi.nlm.nih.gov/pubmed/25051960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-620
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