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PMC, a potent hydrophilic α-tocopherol derivative, inhibits NF-κB activation via PP2A but not IκBα-dependent signals in vascular smooth muscle cells

The hydrophilic α-tocopherol derivative, 2,2,5,7,8-pentamethyl-6-hydroxychromane (PMC), is a promising alternative to vitamin E in clinical applications. Critical vascular inflammation leads to vascular dysfunction and vascular diseases, including atherosclerosis, hypertension and abdominal aortic a...

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Detalhes bibliográficos
Main Authors: Hsieh, Cheng-Ying, Hsiao, George, Hsu, Ming-Jen, Wang, Yi-Hsuan, Sheu, Joen-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124013/
https://ncbi.nlm.nih.gov/pubmed/24725826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12277
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