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The antiplatelet activity of PMC, a potent α-tocopherol analogue, is mediated through inhibition of cyclo-oxygenase
1. PMC, a potent α-tocopherol derivative, dose-dependently (5–25 μM) inhibited the ATP-release reaction and platelet aggregation in washed human platelets stimulated by agonists (collagen and ADP). 2. PMC also dose-dependently inhibited the intracellular Ca(2+) mobilization, whereas it did not inhib...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
1999
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1566113/ https://ncbi.nlm.nih.gov/pubmed/10455267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702637 |
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