Genome-Wide Association Study of Plasma N6 Polyunsaturated Fatty Acids within the CHARGE Consortium

BACKGROUND: Omega-6 (n6) polyunsaturated fatty acids (PUFAs) and their metabolites are involved in cell signaling, inflammation, clot formation, and other crucial biological processes. Genetic components, such as variants of fatty acid desaturase (FADS) genes, determine the composition of n6 PUFAs....

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Main Authors: Guan, Weihua, Steffen, Brian T., Lemaitre, Rozenn N., Wu, Jason H.Y., Tanaka, Toshiko, Manichaikul, Ani, Foy, Millennia, Rich, Stephen S., Wang, Lu, Nettleton, Jennifer A., Tang, Weihong, Gu, Xiangjun, Bandinelli, Stafania, King, Irena B., McKnight, Barbara, Psaty, Bruce M., Siscovick, David, Djousse, Luc, Chen, Yii-Der Ida, Ferrucci, Luigi, Fornage, Myriam, Mozafarrian, Dariush, Tsai, Michael Y., Steffen, Lyn M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123862/
https://ncbi.nlm.nih.gov/pubmed/24823311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.113.000208
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