Molecular Mechanism of Action of Plant DRM De Novo DNA Methyltransferases

DNA methylation is a conserved epigenetic gene regulation mechanism. DOMAINS REARRANGED METHYLTRANSFERASE (DRM) is a key de novo methyltransferase in plants, but how DRM acts mechanistically is poorly understood. Here, we report the crystal structure of the methyltransferase domain of tobacco DRM (N...

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Hlavní autoři: Zhong, Xuehua, Du, Jiamu, Hale, Christopher J., Gallego-Bartolome, Javier, Feng, Suhua, Vashisht, Ajay A., Chory, Joanne, Wohlschlegel, James A., Patel, Dinshaw J., Jacobsen, Steven E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123750/
https://ncbi.nlm.nih.gov/pubmed/24855943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.03.056
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