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Mechanism of DNA methylation-directed histone methylation by KRYPTONITE

In Arabidopsis, CHG DNA methylation is controlled by the H3K9 methylation mark through a self-reinforcing loop between DNA methyltransferase CHROMOMETHYLASE3 (CMT3) and H3K9 histone methyltransferase KRYPTONITE/SUVH4 (KYP). We report on the structure of KYP in complex with methylated DNA, substrate...

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Hlavní autoři: Du, Jiamu, Johnson, Lianna M., Groth, Martin, Feng, Suhua, Hale, Christopher J., Li, Sisi, Vashisht, Ajay A., Wohlschlegel, James A., Patel, Dinshaw J., Jacobsen, Steven E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127122/
https://ncbi.nlm.nih.gov/pubmed/25018018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.06.009
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