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Vascular and neurogenic rejuvenation of the aging mouse brain by young systemic factors

In the adult central nervous system, the vasculature of the neurogenic niche regulates neural stem cell behavior by providing circulating and secreted factors. Age-related decline of neurogenesis and cognitive function is associated with reduced blood flow and decreased numbers of neural stem cells....

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Detalhes bibliográficos
Main Authors: Katsimpardi, Lida, Litterman, Nadia K., Schein, Pamela A., Miller, Christine M., Loffredo, Francesco S., Wojtkiewicz, Gregory R., Chen, John W., Lee, Richard T., Wagers, Amy J., Rubin, Lee L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123747/
https://ncbi.nlm.nih.gov/pubmed/24797482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1251141
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